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St. John’s Wort Influence on Intravenous Fentanyl Pharmacokinetics, Pharmacodynamics and Clinical Effects. A Randomized Clinical Trial.
BACKGROUND: Patients often use complementary and alternative herbal medicines; hence potential exists for adverse herb-drug interactions. Fentanyl is metabolized by hepatic CYP3A4 and considered transported by blood-brain barrier P-glycoprotein. Both disposition processes could be upregulated by the...
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| Udgivet i: | Anesthesiology |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7029805/ https://ncbi.nlm.nih.gov/pubmed/31794512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000003065 |
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