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Pharmacokinetic modelling of the interaction between St John’s wort and ciclosporin A

AIMS: St John’s wort (SJW) decreases the blood concentration of ciclosporin A (CsA), which may result in allograft rejection. In addition, the time course of this interaction is not parallel with the administration of SJW. We aimed to develop a pharmacokinetic model to predict the time profile of bl...

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Detalhes bibliográficos
Main Authors: Murakami, Yuichi, Tanaka, Tomoaki, Murakami, Hideyasu, Tsujimoto, Masayuki, Ohtani, Hisakazu, Sawada, Yasufumi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885115/
https://ncbi.nlm.nih.gov/pubmed/16722827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02606.x
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