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Sox2 Level Is a Determinant of Cellular Reprogramming Potential

Epiblast stem cells (EpiSCs) and embryonic stem cells (ESCs) differ in their in vivo differentiation potential. While ESCs form teratomas and efficiently contribute to the development of chimeras, EpiSCs form teratomas but very rarely chimeras. In contrast to their differentiation potential, the rep...

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Detalhes bibliográficos
Main Authors: Han, Dong Wook, Tapia, Natalia, Araúzo-Bravo, Marcos J., Lim, Kyung Tae, Kim, Kee Pyo, Ko, Kinarm, Lee, Hoon Taek, Schöler, Hans R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688988/
https://ncbi.nlm.nih.gov/pubmed/23825671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067594
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