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Sox2 Level Is a Determinant of Cellular Reprogramming Potential

Epiblast stem cells (EpiSCs) and embryonic stem cells (ESCs) differ in their in vivo differentiation potential. While ESCs form teratomas and efficiently contribute to the development of chimeras, EpiSCs form teratomas but very rarely chimeras. In contrast to their differentiation potential, the rep...

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Autors principals: Han, Dong Wook, Tapia, Natalia, Araúzo-Bravo, Marcos J., Lim, Kyung Tae, Kim, Kee Pyo, Ko, Kinarm, Lee, Hoon Taek, Schöler, Hans R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688988/
https://ncbi.nlm.nih.gov/pubmed/23825671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067594
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