Lataa...

Efficacious Cyclic N-Acyl O-Amino Phenol Duocarmycin Prodrugs

Two novel cyclic N-acyl O-amino phenol prodrugs are reported as new members of a unique class of reductively cleaved prodrugs of the duocarmycin family of natural products. These prodrugs were explored with the expectation that they may be cleaved selectively within hypoxic tumor environments that h...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wolfe, Amanda L., Duncan, Katharine K., Parelkar, Nikhil K., Brown, Douglas, Vielhauer, George A., Boger, Dale L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687800/
https://ncbi.nlm.nih.gov/pubmed/23627265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400413r
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!