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Reassembly of functionally intact environmental DNA-derived biosynthetic gene clusters

Only a small fraction of the bacterial diversity present in natural microbial communities is regularly cultured in the laboratory. Those bacteria that remain recalcitrant to culturing cannot be examined for the production of bioactive secondary metabolites using standard pure-culture approaches. The...

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Detalhes bibliográficos
Main Authors: Kallifidas, Dimitris, Brady, Sean F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687798/
https://ncbi.nlm.nih.gov/pubmed/23084941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-404634-4.00011-5
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