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Tetarimycin A, an MRSA active antibiotic identified through induced expression of environmental DNA gene clusters

The propagation of DNA extracted directly from environmental samples in laboratory grown bacteria provides a means to study natural products encoded in the genomes of uncultured bacteria. Gene silencing however, often hampers functional characterization of gene clusters captured on environmental DNA...

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Detalhes bibliográficos
Main Authors: Kallifidas, Dimitris, Kang, Hahk-Soo, Brady, Sean F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540986/
https://ncbi.nlm.nih.gov/pubmed/23157252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3093828
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