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Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites

A single gram of soil is predicted to contain thousands of unique bacterial species. The majority of these species remain recalcitrant to standard culture methods, prohibiting their use as sources of unique bioactive small molecules. The cloning and analysis of DNA extracted directly from environmen...

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Detalhes bibliográficos
Main Authors: Feng, Zhiyang, Kallifidas, Dimitris, Brady, Sean F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150919/
https://ncbi.nlm.nih.gov/pubmed/21768346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103921108
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