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Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived Type II PKS gene cluster

[Image: see text] Culture independent approaches for accessing small molecules produced by uncultured bacteria are often hampered by the inability to easily clone environmental DNA (eDNA) fragments large enough to capture intact biosynthetic gene clusters that can be used in heterologous expression...

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Detalhes bibliográficos
Main Authors: Feng, Zhiyang, Kim, Jeff H., Brady, Sean F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930618/
https://ncbi.nlm.nih.gov/pubmed/20690632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104550p
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