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Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived Type II PKS gene cluster

[Image: see text] Culture independent approaches for accessing small molecules produced by uncultured bacteria are often hampered by the inability to easily clone environmental DNA (eDNA) fragments large enough to capture intact biosynthetic gene clusters that can be used in heterologous expression...

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Bibliografske podrobnosti
Main Authors: Feng, Zhiyang, Kim, Jeff H., Brady, Sean F.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930618/
https://ncbi.nlm.nih.gov/pubmed/20690632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104550p
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