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Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived Type II PKS gene cluster

[Image: see text] Culture independent approaches for accessing small molecules produced by uncultured bacteria are often hampered by the inability to easily clone environmental DNA (eDNA) fragments large enough to capture intact biosynthetic gene clusters that can be used in heterologous expression...

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Sonraí Bibleagrafaíochta
Main Authors: Feng, Zhiyang, Kim, Jeff H., Brady, Sean F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930618/
https://ncbi.nlm.nih.gov/pubmed/20690632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104550p
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