Comparison of two CD40-ligand/interleukin-2 vaccines in patients with chronic lymphocytic leukemia

BACKGROUND AIMS: Several studies have demonstrated that the immunogenicity of chronic lymphocytic leukemia (CLL) cells can be increased by manipulation of the CD40/CD40-ligand (CD40L) pathway. Although immunologic, and perhaps clinical, benefits have been obtained with an autologous CLL tumor vaccin...

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Huvudupphovsmän: Okur, Fatma Visal, Yvon, Eric, Biagi, Ettore, Dotti, Gianpietro, Carrum, George, Heslop, Helen, Mims, Martha P., Fratantoni, Joseph C., Peshwa, Madhusudan V., Li, Linhong, Brenner, Malcolm K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687103/
https://ncbi.nlm.nih.gov/pubmed/21745159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653249.2011.592523
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