Selective Elimination of a Chemoresistant Side-Population of B-CLL Cells by Cytotoxic T Lymphocytes in Subjects Receiving an Autologous hCD40L/IL-2 Tumor Vaccine

Side-population (SP) analysis identifies precursor cells in normal and malignant tissues. Cells with this phenotype have increased resistance to many cytotoxic agents, and in malignant disease may represent a primary drug resistant population. To discover whether drug resistant malignant SP cells ar...

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Main Authors: Foster, Aaron E, Okur, Fatma V, Biagi, Ettore, Lu, An, Dotti, Gianpietro, Yvon, Eric, Savoldo, Barbara, Carrum, George, Goodell, Margaret A, Heslop, Helen E, Brenner, Malcolm K
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836398/
https://ncbi.nlm.nih.gov/pubmed/20072155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.281
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