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Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression

Cancer precursor/progenitor cells may initiate and sustain the growth of tumors, but evidence for their existence in human disease is indirect, relying on their in vitro properties and animal models. More directly, specific elimination of these rare cells from cancer patients should produce a delaye...

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Detalhes bibliográficos
Main Authors: Foster, Aaron E, Okur, Fatma V, Biagi, Ettore, Lu, An, Dotti, Gianpietro, Yvon, Eric, Savoldo, Barbara, Carrum, George, Andreeff, Michael, Goodell, Margaret A, Heslop, Helen E, Brenner, Malcolm K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784756/
https://ncbi.nlm.nih.gov/pubmed/19922650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-106
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