Induction of Antigen-Specific Regulatory T Cells following Overexpression of a Notch Ligand by Human B Lymphocytes

In mice, activation of the Notch pathway in T cells by antigen-presenting cells overexpressing Notch ligands favors differentiation of regulatory T lymphocytes responsible for antigen-specific tolerance. To determine whether this mechanism operates in human T cells, we used Epstein-Barr virus-positi...

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Detalhes bibliográficos
Main Authors: Vigouroux, Stéphane, Yvon, Eric, Wagner, Hans-Joachim, Biagi, Ettore, Dotti, Gianpietro, Sili, Uluhan, Lira, Cecilia, Rooney, Cliona M., Brenner, Malcolm K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224961/
https://ncbi.nlm.nih.gov/pubmed/14512537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.10872-10880.2003
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