ATM kinase inhibition preferentially sensitizes p53 mutant glioma to ionizing radiation

PURPOSE: Glioblastoma multiforme (GBM) is the most lethal form of brain cancer with a median survival of only 12–15 months. Current standard treatment consists of surgery followed by chemoradiation. The poor survival of GBM patients is due to aggressive tumor invasiveness, an inability to remove all...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Biddlestone-Thorpe, Laura, Sajjad, Muhammad, Rosenberg, Elizabeth, Beckta, Jason M., Valerie, Nicholas C.K., Tokarz, Mary, Adams, Bret R., Wagner, Alison F., Khalil, Ashraf, Gilfor, Donna, Golding, Sarah E., Deb, Sumitra, Temesi, David G., Lau, Alan, O'Connor, Mark J., Choe, Kevin S., Parada, Luis F., Lim, Sang Kyun, Mukhopadhyay, Nitai D., Valerie, Kristoffer
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687028/
https://ncbi.nlm.nih.gov/pubmed/23620409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3408
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki