The effect of copy number variation (CNV) in the phase II detoxification genes, UGT2B17 and UGT2B28, on colorectal cancer risk

BACKGROUND: Genetic polymorphisms in combination with the Western-style diet, physical inactivity, smoking, excessive alcohol consumption, and obesity have been hypothesized to affect colorectal cancer (CRC) risk. Metabolizers of environmental carcinogenic and endogenous compounds affecting CRC risk...

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Autori principali: Angstadt, Andrea Y., Berg, Arthur, Zhu, Junjia, Miller, Paige, Hartman, Terryl J., Lesko, Samuel M., Muscat, Joshua E., Lazarus, Philip, Gallagher, Carla J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686841/
https://ncbi.nlm.nih.gov/pubmed/23575887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28009
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