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Simultaneous Targeting of Tumor Antigens and the Tumor Vasculature using T Lymphocyte Transfer Synergize to Induce Regression of Established Tumors in Mice

Most systemic cancer therapies target tumor cells directly though there is increasing interest in targeting the tumor stroma that can comprise a substantial portion of the tumor mass. We report here a synergy between two T cell therapies, one directed against the stromal tumor vasculature and the ot...

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Bibliographische Detailangaben
Hauptverfasser: Chinnasamy, Dhanalakshmi, Tran, Eric, Yu, Zhiya, Morgan, Richard A., Restifo, Nicholas P., Rosenberg, Steven A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686092/
https://ncbi.nlm.nih.gov/pubmed/23633494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3913
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