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Two forms of loops generate the chromatin conformation of the immunoglobulin heavy chain gene locus
The immunoglobulin heavy chain (IgH) gene locus undergoes radial re-positioning within the nucleus and locus contraction in preparation for gene recombination. We demonstrate that IgH locus conformation involves two levels of chromosomal compaction. At the first level the locus folds into several mu...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3685183/ https://ncbi.nlm.nih.gov/pubmed/21982154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.08.049 |
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