Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells

The immunoglobulin heavy-chain (IgH) locus undergoes large-scale contraction in B cells poised to undergo IgH V(D)J recombination. We considered the possibility that looping of distinct IgH V regions plays a role in promoting long-range interactions. Here, we simultaneously visualize three subregion...

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Enregistré dans:
Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Sayegh, Camil, Jhunjhunwala, Suchit, Riblet, Roy, Murre, Cornelis
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2005
Sujets:
Research Communications
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC546510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15687256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1254305
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