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Three Ubiquitination Sites of Organic Anion Transporter-1 Synergistically Mediate Protein Kinase C–Dependent Endocytosis of the Transporter
Organic anion transporter–1 (OAT1) mediates the body disposition of a diverse array of clinically important drugs, including anti-HIV therapeutics, antitumor drugs, antibiotics, antihypertensives, and anti-inflammatories. Therefore, understanding the regulation of OAT1 has profound clinical signific...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684823/ https://ncbi.nlm.nih.gov/pubmed/23640180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.086769 |
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