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Regulation of Human Organic Anion Transporter 4 by Protein Kinase C and NHERF-1: Altering the Endocytosis of the Transporter

PURPOSE: Human organic anion transporter 4 (hOAT4) belongs to a family of organic anion transporters that play critical roles in the body disposition of clinically important drugs. We have previously shown that the activity of hOAT4 was down-regulated by activation of PKC and up-regulated by PDZ pro...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Zhang, Qiang, Pan, Zui, You, Guofeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5169165/
https://ncbi.nlm.nih.gov/pubmed/20140636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9983-2
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