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Nedd4-2 but not Nedd4-1 is critical for protein kinase C-regulated ubiquitination, expression, and transport activity of human organic anion transporter 1

Human organic anion transporter 1 (hOAT1) expressed at the membrane of the kidney proximal tubule cells mediates the body disposition of a diverse array of clinically important drugs, including anti-HIV therapeutics, antitumor drugs, antibiotics, antihypertensives, and antiinflammatories. Therefore,...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Xu, Da, Wang, Haoxun, Zhang, Qiang, You, Guofeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867312/
https://ncbi.nlm.nih.gov/pubmed/26823285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00522.2015
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