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Lysine 48-Linked Polyubiquitination of Organic Anion Transporter-1 Is Essential for Its Protein Kinase C–Regulated Endocytosis
Organic anion transporter-1 (OAT1) mediates the body’s disposition of a diverse array of environmental toxins and clinically important drugs. Therefore, understanding the regulation of this transporter has profound clinical significance. We had previously established that OAT1 undergoes constitutive...
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Huvudupphovsmän: | , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533473/ https://ncbi.nlm.nih.gov/pubmed/23087261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.082065 |
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