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Lysine 48-Linked Polyubiquitination of Organic Anion Transporter-1 Is Essential for Its Protein Kinase C–Regulated Endocytosis

Organic anion transporter-1 (OAT1) mediates the body’s disposition of a diverse array of environmental toxins and clinically important drugs. Therefore, understanding the regulation of this transporter has profound clinical significance. We had previously established that OAT1 undergoes constitutive...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Qiang, Li, Shanshan, Patterson, Cam, You, Guofeng
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533473/
https://ncbi.nlm.nih.gov/pubmed/23087261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.082065
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