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Three Ubiquitin Conjugation Sites in the Amino Terminus of the Dopamine Transporter Mediate Protein Kinase C–dependent Endocytosis of the Transporter

Dopamine levels in the brain are controlled by the plasma membrane dopamine transporter (DAT). The amount of DAT at the cell surface is determined by the relative rates of its internalization and recycling. Activation of protein kinase C (PKC) leads to acceleration of DAT endocytosis. We have recent...

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Detalhes bibliográficos
Main Authors: Miranda, Manuel, Dionne, Kalen R., Sorkina, Tatiana, Sorkin, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751334/
https://ncbi.nlm.nih.gov/pubmed/17079728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0704
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