c-IAP1 and c-IAP2 Redundancy Differs between T and B Cells

Cellular Inhibitors of Apoptosis 1 and 2 (c-IAP1 and c-IAP2) are ubiquitin protein ligases (E3s) that constitutively ubiquitinate and induce proteasomal-mediated degradation of NF-κB Inducing Kinase (NIK) and repress non-canonical NF-κB activation. Mice expressing an E3-inactive c-IAP2 mutant (c-IAP...

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Bibliographic Details
Main Authors: Giardino Torchia, Maria Letizia, Conze, Dietrich B., Ashwell, Jonathan D.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684576/
https://ncbi.nlm.nih.gov/pubmed/23799077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066161
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