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Roles Nrf2 Plays in Myeloid Cells and Related Disorders

The Keap1-Nrf2 system protects animals from oxidative and electrophilic stresses. Nrf2 is a transcription factor that induces the expression of genes essential for detoxifying reactive oxygen species (ROS) and cytotoxic electrophiles. Keap1 is a stress sensor protein that binds to and ubiquitinates...

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Detalhes bibliográficos
Main Authors: Kobayashi, Eri, Suzuki, Takafumi, Yamamoto, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684031/
https://ncbi.nlm.nih.gov/pubmed/23819012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/529219
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