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Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes

Nrf1 is a member of the vertebrate Cap`n'Collar (CNC) transcription factor family that commonly contains a unique basic-leucine zipper domain. Among CNC family members, Nrf2 is known to regulate a battery of antioxidant and xenobiotic-metabolizing enzyme genes through the antioxidant response e...

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Bibliographische Detailangaben
Hauptverfasser: Ohtsuji, Makiko, Katsuoka, Fumiki, Kobayashi, Akira, Aburatani, Hiroyuki, Hayes, John D., Yamamoto, Masayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662273/
https://ncbi.nlm.nih.gov/pubmed/18826952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804597200
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