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Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks
NF-E2-related factor 2 (Nrf2) is a key transcription factor that is critical for cellular defense against oxidative and xenobiotic insults. Nrf2 heterodimerizes with small Maf (sMaf) proteins and binds to antioxidant response elements (AREs) to activate a battery of cytoprotective genes. However, it...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488259/ https://ncbi.nlm.nih.gov/pubmed/22965115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks827 |
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