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Roles Nrf2 Plays in Myeloid Cells and Related Disorders
The Keap1-Nrf2 system protects animals from oxidative and electrophilic stresses. Nrf2 is a transcription factor that induces the expression of genes essential for detoxifying reactive oxygen species (ROS) and cytotoxic electrophiles. Keap1 is a stress sensor protein that binds to and ubiquitinates...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Hindawi Publishing Corporation
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684031/ https://ncbi.nlm.nih.gov/pubmed/23819012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/529219 |
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