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Enhanced Expression of the Transcription Factor Nrf2 by Cancer Chemopreventive Agents: Role of Antioxidant Response Element-Like Sequences in the nrf2 Promoter

Induction of phase 2 enzymes, which neutralize reactive electrophiles and act as indirect antioxidants, is an important mechanism for protection against carcinogenesis. The transcription factor Nrf2, which binds to the antioxidant response element (ARE) found in the upstream regulatory region of man...

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Detalhes bibliográficos
Main Authors: Kwak, Mi-Kyoung, Itoh, Ken, Yamamoto, Masayuki, Kensler, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133753/
https://ncbi.nlm.nih.gov/pubmed/11940647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.9.2883-2892.2002
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