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Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway

Proteasomes degrade damaged proteins formed during oxidative stress, thereby promoting cell survival. Neurodegenerative and other age-related disorders are associated with reduced proteasome activity. We show herein that expression of most subunits of 20S and 19S proteasomes, which collectively asse...

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Библиографические подробности
Главные авторы: Kwak, Mi-Kyoung, Wakabayashi, Nobunao, Greenlaw, Jennifer L., Yamamoto, Masayuki, Kensler, Thomas W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC262680/
https://ncbi.nlm.nih.gov/pubmed/14612418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8786-8794.2003
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