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Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet

The Keap1/Nrf2 pathway, known to regulate the expression of a series of cytoprotective and antioxidant genes, has been studied in the context of obesity and type 2 diabetes; diseases that are characterized by chronic oxidative stress. There is increasing evidence, however, that the transcription fac...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arch Biochem Biophys
Egile Nagusiak: Slocum, Stephen L., Skoko, John J., Wakabayashi, Nobunao, Aja, Susan, Yamamoto, Masayuki, Kensler, Thomas W., Chartoumpekis, Dionysios V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747866/
https://ncbi.nlm.nih.gov/pubmed/26701603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2015.11.040
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