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The roles of 3′-exoribonucleases and the exosome in trypanosome mRNA degradation
The degradation of eukaryotic mRNAs can be initiated by deadenylation, decapping, or endonuclease cleavage. This is followed by 5′–3′ degradation by homologs of Xrn1, and/or 3′–5′ degradation by the exosome. We previously reported that, in African trypanosome Trypanosoma brucei, most mRNAs are deade...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683928/ https://ncbi.nlm.nih.gov/pubmed/23697549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.038430.113 |
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