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The role of the 5′–3′ exoribonuclease XRNA in transcriptome-wide mRNA degradation

The steady-state level of each mRNA in a cell is a balance between synthesis and degradation. Here, we use high-throughput RNA sequencing (RNASeq) to determine the relationship between mRNA degradation and mRNA abundance on a transcriptome-wide scale. The model organism used was the bloodstream form...

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Bibliografiske detaljer
Main Authors: Manful, Theresa, Fadda, Abeer, Clayton, Christine
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198596/
https://ncbi.nlm.nih.gov/pubmed/21947264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2837311
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