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RNA polymerase approaches its promoter without long-range sliding along DNA
Sequence-specific DNA binding proteins must quickly bind target sequences, despite the enormously larger amount of nontarget DNA present in cells. RNA polymerases (or associated general transcription factors) are hypothesized to reach promoter sequences by facilitated diffusion (FD). In FD, a protei...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683791/ https://ncbi.nlm.nih.gov/pubmed/23720315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300221110 |
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