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RNA polymerase approaches its promoter without long-range sliding along DNA

Sequence-specific DNA binding proteins must quickly bind target sequences, despite the enormously larger amount of nontarget DNA present in cells. RNA polymerases (or associated general transcription factors) are hypothesized to reach promoter sequences by facilitated diffusion (FD). In FD, a protei...

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Bibliografske podrobnosti
Main Authors: Friedman, Larry J., Mumm, Jeffrey P., Gelles, Jeff
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683791/
https://ncbi.nlm.nih.gov/pubmed/23720315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300221110
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