Dynamics of RNA polymerase II and elongation factor Spt4/5 recruitment during activator-dependent transcription

In eukaryotes, RNA polymerase II (RNApII) transcribes messenger RNA from template DNA. Decades of experiments have identified the proteins needed for transcription activation, initiation complex assembly, and productive elongation. However, the dynamics of recruitment of these proteins to transcript...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Rosen, Grace A., Baek, Inwha, Friedman, Larry J., Joo, Yoo Jin, Buratowski, Stephen, Gelles, Jeff
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768755/
https://ncbi.nlm.nih.gov/pubmed/33293419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011224117
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