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Tension modulates actin filament polymerization mediated by formin and profilin

Formins promote processive elongation of actin filaments for cytokinetic contractile rings and other cellular structures. In vivo, these structures are exposed to tension, but the effect of tension on these processes was unknown. Here we used single-molecule imaging to investigate the effects of ten...

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Autores principales: Courtemanche, Naomi, Lee, Ja Yil, Pollard, Thomas D., Greene, Eric C.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683744/
https://ncbi.nlm.nih.gov/pubmed/23716666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308257110
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