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The Role of the FH1 Domain and Profilin in Formin-Mediated Actin-Filament Elongation and Nucleation

BACKGROUND: Formin proteins nucleate actin filaments de novo and stay associated with the growing barbed end. Whereas the formin-homology (FH) 2 domains mediate processive association, the FH1 domains—in concert with the actin-monomer-binding protein profilin—increase the rate of barbed-end elongati...

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Bibliografski detalji
Glavni autori: Paul, Aditya, Pollard, Thomas
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712528/
https://ncbi.nlm.nih.gov/pubmed/18160294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.11.062
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