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The Role of the FH1 Domain and Profilin in Formin-Mediated Actin-Filament Elongation and Nucleation
BACKGROUND: Formin proteins nucleate actin filaments de novo and stay associated with the growing barbed end. Whereas the formin-homology (FH) 2 domains mediate processive association, the FH1 domains—in concert with the actin-monomer-binding protein profilin—increase the rate of barbed-end elongati...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712528/ https://ncbi.nlm.nih.gov/pubmed/18160294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.11.062 |
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