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Competition for delivery of profilin–actin to barbed ends limits the rate of formin-mediated actin filament elongation
Formins direct the elongation of unbranched actin filaments by binding their barbed ends and processively stepping onto incoming actin monomers to incorporate them into the filament. Binding of profilin to actin monomers creates profilin–actin complexes, which then bind polyproline tracts located in...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7135983/ https://ncbi.nlm.nih.gov/pubmed/32075907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012000 |
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