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Competition for delivery of profilin–actin to barbed ends limits the rate of formin-mediated actin filament elongation

Formins direct the elongation of unbranched actin filaments by binding their barbed ends and processively stepping onto incoming actin monomers to incorporate them into the filament. Binding of profilin to actin monomers creates profilin–actin complexes, which then bind polyproline tracts located in...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Zweifel, Mark E., Courtemanche, Naomi
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7135983/
https://ncbi.nlm.nih.gov/pubmed/32075907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012000
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