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Competition for delivery of profilin–actin to barbed ends limits the rate of formin-mediated actin filament elongation
Formins direct the elongation of unbranched actin filaments by binding their barbed ends and processively stepping onto incoming actin monomers to incorporate them into the filament. Binding of profilin to actin monomers creates profilin–actin complexes, which then bind polyproline tracts located in...
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| Gepubliceerd in: | J Biol Chem |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7135983/ https://ncbi.nlm.nih.gov/pubmed/32075907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012000 |
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