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Tension modulates actin filament polymerization mediated by formin and profilin

Formins promote processive elongation of actin filaments for cytokinetic contractile rings and other cellular structures. In vivo, these structures are exposed to tension, but the effect of tension on these processes was unknown. Here we used single-molecule imaging to investigate the effects of ten...

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Détails bibliographiques
Auteurs principaux: Courtemanche, Naomi, Lee, Ja Yil, Pollard, Thomas D., Greene, Eric C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683744/
https://ncbi.nlm.nih.gov/pubmed/23716666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308257110
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