Local Overexpression of Interleukin-11 in the Central Nervous System Limits Demyelination and Enhances Remyelination

Demyelination is one of the pathological hallmarks of multiple sclerosis (MS). To date, no therapy is available which directly potentiates endogenous remyelination. Interleukin-11 (IL-11), a member of the gp130 family of cytokines, is upregulated in MS lesions. Systemic IL-11 treatment was shown to...

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書誌詳細
主要な著者: Maheshwari, Anurag, Janssens, Kris, Bogie, Jeroen, Van Den Haute, Chris, Struys, Tom, Lambrichts, Ivo, Baekelandt, Veerle, Stinissen, Piet, Hendriks, Jerome J. A., Slaets, Helena, Hellings, Niels
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683504/
https://ncbi.nlm.nih.gov/pubmed/23818742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/685317
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