Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination

The brain’s endogenous capacity to restore damaged myelin deteriorates during the course of demyelinating disorders. Currently, no treatment options are available to establish remyelination. Chronic demyelination leads to damaged axons and irreversible destruction of the central nervous system (CNS)...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Houben, Evelien, Janssens, Kris, Hermans, Doryssa, Vandooren, Jennifer, Van den Haute, Chris, Schepers, Melissa, Vanmierlo, Tim, Lambrichts, Ivo, van Horssen, Jack, Baekelandt, Veerle, Opdenakker, Ghislain, Baron, Wia, Broux, Bieke, Slaets, Helena, Hellings, Niels
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060743/
https://ncbi.nlm.nih.gov/pubmed/32071226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912910117
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