Helix Unfolding/Refolding Characterizes the Functional Dynamics of Staphylococcus aureus Clp Protease

The ATP-dependent Clp protease (ClpP) plays an essential role not only in the control of protein quality but also in the regulation of bacterial pathogen virulence, making it an attractive target for antibacterial treatment. We have previously determined the crystal structures of Staphylococcus aure...

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Detalles Bibliográficos
Main Authors: Ye, Fei, Zhang, Jie, Liu, Hongchuan, Hilgenfeld, Rolf, Zhang, Ruihan, Kong, Xiangqian, Li, Lianchun, Lu, Junyan, Zhang, Xinlei, Li, Donghai, Jiang, Hualiang, Yang, Cai-Guang, Luo, Cheng
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Computational Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682565/
https://ncbi.nlm.nih.gov/pubmed/23625918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452714
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