Helix Unfolding/Refolding Characterizes the Functional Dynamics of Staphylococcus aureus Clp Protease

The ATP-dependent Clp protease (ClpP) plays an essential role not only in the control of protein quality but also in the regulation of bacterial pathogen virulence, making it an attractive target for antibacterial treatment. We have previously determined the crystal structures of Staphylococcus aure...

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Bibliografski detalji
Glavni autori: Ye, Fei, Zhang, Jie, Liu, Hongchuan, Hilgenfeld, Rolf, Zhang, Ruihan, Kong, Xiangqian, Li, Lianchun, Lu, Junyan, Zhang, Xinlei, Li, Donghai, Jiang, Hualiang, Yang, Cai-Guang, Luo, Cheng
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Computational Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682565/
https://ncbi.nlm.nih.gov/pubmed/23625918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452714
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