Helix Unfolding/Refolding Characterizes the Functional Dynamics of Staphylococcus aureus Clp Protease

The ATP-dependent Clp protease (ClpP) plays an essential role not only in the control of protein quality but also in the regulation of bacterial pathogen virulence, making it an attractive target for antibacterial treatment. We have previously determined the crystal structures of Staphylococcus aure...

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Bibliografiske detaljer
Main Authors: Ye, Fei, Zhang, Jie, Liu, Hongchuan, Hilgenfeld, Rolf, Zhang, Ruihan, Kong, Xiangqian, Li, Lianchun, Lu, Junyan, Zhang, Xinlei, Li, Donghai, Jiang, Hualiang, Yang, Cai-Guang, Luo, Cheng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Computational Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682565/
https://ncbi.nlm.nih.gov/pubmed/23625918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452714
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