Helix Unfolding/Refolding Characterizes the Functional Dynamics of Staphylococcus aureus Clp Protease

The ATP-dependent Clp protease (ClpP) plays an essential role not only in the control of protein quality but also in the regulation of bacterial pathogen virulence, making it an attractive target for antibacterial treatment. We have previously determined the crystal structures of Staphylococcus aure...

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Bibliografische gegevens
Hoofdauteurs: Ye, Fei, Zhang, Jie, Liu, Hongchuan, Hilgenfeld, Rolf, Zhang, Ruihan, Kong, Xiangqian, Li, Lianchun, Lu, Junyan, Zhang, Xinlei, Li, Donghai, Jiang, Hualiang, Yang, Cai-Guang, Luo, Cheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
Onderwerpen:
Computational Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682565/
https://ncbi.nlm.nih.gov/pubmed/23625918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452714
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