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Identification of the β-Lactamase Inhibitor Protein-II (BLIP-II) Interface Residues Essential for Binding Affinity and Specificity for Class A β-Lactamases

The interactions between β-lactamase inhibitory proteins (BLIPs) and β-lactamases have been used as model systems to understand the principles of affinity and specificity in protein-protein interactions. The most extensively studied tight binding inhibitor, BLIP, has been characterized with respect...

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Main Authors: Brown, Nicholas G., Chow, Dar-Chone, Ruprecht, Kevin E., Palzkill, Timothy
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682521/
https://ncbi.nlm.nih.gov/pubmed/23625930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.463521
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