AML1-ETO mediates hematopoietic self-renewal and leukemogenesis through a COX/β-catenin signaling pathway

Developing novel therapies that suppress self-renewal of leukemia stem cells may reduce the likelihood of relapses and extend long-term survival of patients with acute myelogenous leukemia (AML). AML1-ETO (AE) is an oncogene that plays an important role in inducing self-renewal of hematopoietic stem...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Yiyun, Wang, Jianfeng, Wheat, Justin, Chen, Xi, Jin, Shan, Sadrzadeh, Hossein, Fathi, Amir T., Peterson, Randall T., Kung, Andrew L., Sweetser, David A., Yeh, Jing-Ruey Joanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Myeloid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682341/
https://ncbi.nlm.nih.gov/pubmed/23645839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-447763
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