Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival

Deletions on chromosome 9q are seen in a subset of acute myeloid leukemia (AML) cases and are specifically associated with t(8;21) AML. We previously defined the commonly deleted region in del(9q) AML and characterized the genes in this interval. To determine the critical lost gene(s) that might coo...

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Autori principali: Dayyani, Farshid, Wang, Jianfeng, Yeh, Jing-Ruey J., Ahn, Eun-Young, Tobey, Erica, Zhang, Dong-Er, Bernstein, Irwin D., Peterson, Randall T., Sweetser, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
Soggetti:
Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288729/
https://ncbi.nlm.nih.gov/pubmed/18258796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-103291
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