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Novel mechanism of regulation of fibrosis in kidney tumor with tuberous sclerosis

BACKGROUND: Deficiency in tuberin results in activation the mTOR pathway and leads to accumulation of cell matrix proteins. The mechanisms by which tuberin regulates fibrosis in kidney angiomyolipomas (AMLs) of tuberous sclerosis patients are not fully known. METHOD: In the present study, we investi...

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Main Authors: Liang, Sitai, Cuevas, Gabriela, Tizani, Shaza, Salas, Tiffanie, Liu, Huijuan, Li, Baojie, Habib, Samy L
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681649/
https://ncbi.nlm.nih.gov/pubmed/23705901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-49
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