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Novel mechanism of regulation of fibrosis in kidney tumor with tuberous sclerosis

BACKGROUND: Deficiency in tuberin results in activation the mTOR pathway and leads to accumulation of cell matrix proteins. The mechanisms by which tuberin regulates fibrosis in kidney angiomyolipomas (AMLs) of tuberous sclerosis patients are not fully known. METHOD: In the present study, we investi...

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מידע ביבליוגרפי
Main Authors: Liang, Sitai, Cuevas, Gabriela, Tizani, Shaza, Salas, Tiffanie, Liu, Huijuan, Li, Baojie, Habib, Samy L
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681649/
https://ncbi.nlm.nih.gov/pubmed/23705901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-49
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