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Tuberin regulates reactive oxygen species in renal proximal cells, kidney from rodents, and kidney from patients with tuberous sclerosis complex

Reactive oxygen species (ROS) are an important endogenous source of DNA damage and oxidative stress in all cell types. Deficiency in tuberin resulted in increased oxidative DNA damage in renal cells. In this study, the role of tuberin in the regulating of ROS and NADPH oxidases was investigated. For...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Habib, Samy L., Abboud, Hanna E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982584/
https://ncbi.nlm.nih.gov/pubmed/27278252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12984
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